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Single cell research and microfluidics in 2023 – an…

ChatGPT, the trained model for open conversations by OpenAI has taken over the internet in recent weeks, used for fun things, such as having...
Juliane Fischer
5 min read

A year of new tools and developments – read…

With 2022 coming to an end, we wanted to reflect on everything exciting that happened in our Dolomite Bio community. In particular, we wanted...
Juliane Fischer
2 min read

Disclosing transcriptional profiles of a conserved GI stromal stem…

Single cell study for the population and signaling pathways of gastrointestinal stem cells niches In the human body, the development of distinct organs is...
Xuan Nguyen
3 min read

Custom Microfluidics – Powering your research with Nadia Go

History of microfluidics A plethora of biological techniques have been developed in the past decade which allows the study of a large cell population....
Vanessa Lobo
3 min read

Custom protocol development – introducing the Nadia Go

The Nadia Go – an open microfluidic system We are pleased to announce the new addition to the Nadia product family—The Nadia Go, which...
Vanessa Lobo
3 min read

Cell annotation in single cell data analysis

The main goal, and challenge, in single-cell RNA sequencing data analysis is assigning cell type identity to cells. Performed after dimensionality reduction and clustering,...
Xuan Nguyen
4 min read

5 things you need to know about 3D Cell…

A (Very) Brief History of 3D cell culture The earliest studies related to 3D cell culture in the 80s highlighted the importance of 3D...
Vanessa Lobo
3 min read

Using hydrogels in single cell research- getting started with…

An out-and-out solution for Agarose Encapsulation The ideal habitat for cells The holy grail of cell culture methods would combine the high throughput encapsulation...
Vanessa Lobo
5 min read

UMAP method- Dimensionality Reduction in Single Cell Genomics

Dimension reduction methods – UMAP In the previous blog, we introduced dimension reduction in single cell RNA-Sequencing (scRNA-Seq) as well as PCA and t-SNE...
Xuan Nguyen
3 min read

Dimensionality Reduction in Single Cell Genomics

What is dimensionality reduction? Introduced in 2009, single-cell RNA sequencing (scRNA-Seq) allows researchers to observe cellular heterogeneity of the transcriptome at the resolution of...
Xuan Nguyen
2 min read