Juliane Fischer As a Technical Application Specialist, Juliane is responsible for a range of application work including producing application notes, technical copy and running demos, workshops and webinars. Prior to this, Juliane gained her PhD at Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany in Chromatin remodelling during a fungal‐bacterial interaction.

7th Annual Single Cell Analysis Congress, London, Highlights

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The Single Cell Analysis Congress took place last week in London, UK. Paul Oakley, our Regional Manager for Europe, Muriel Breteau, Nadia Shakir and Juliane Fischer, three of our Application Specialists and two of our Research Biologists, were lucky enough to join this meeting.

The conference had an excellent array of speakers, with talks from some of the best-known names in the single cell community, including: Roman Zubarev, Akos Vertes and Klaas Mulder to name a few. One of the many hot topics during this meeting centered around multi-omics and multi-prolonged approaches as well as spatial transcriptomics.

 

Our highlights from the 7th Annual Single Cell Analysis Congress

This first day began with an array of talks, including presentations from Florian Rambow, Stephen Clark and Bart Westendorp.  One fascinating talk was on High Through-Put Single Cell Metabolomics from Akos Vertes; who demonstrated a robust method for single cell metabolomics using Laser Ablation Electro Spray Ionization.

The second day showcased similar themes but this time focusing more on antibody discovery and single cell data analysis. With talks from Caroline Gubser Kelleron Data Powered Drug Discovery, and Klaas Mulder on RAID-seq – a method for intracellular (phospho-)protein quantification combined with RNA-seq from single cells.

The conference ended on Friday with some great sessions covering the hot topic of single cell applications in therapeutic discovery and development. With talks on deep mining of the antibody repertoire and T-cell heterogeneity. Rounded up by parallel stream on single cell data analysis, detailing some of the analysis challenges that the field faces. As well as the newest developments, such as the introduction of the new single cell data analysis tool, SCHNAPPs.

During the event, Dolomite Bio, also launched their newest application note “Encapsulating single cells in agarose”. Using the Nadia Innovate, single cells can now be encapsulated in agarose and grown for long periods of time within these individual microenvironments. This approach permits a range of research into various scientific fields, including single cell research. When undertaking cancer research, encapsulating single cells in agarose is particularly beneficial to study tumor development, drug screening-once colonies of cancer cells are established and growing single cells in gel spheres; which can also facilitate cell seeding onto 3D scaffolds to form hydrogel matrices for in vitro tissue synthesis.

To find out more, or to download our newest application note, please visit our application page.

 

Early next year, we will also be attending AGBT 2020!

 

Juliane Fischer As a Technical Application Specialist, Juliane is responsible for a range of application work including producing application notes, technical copy and running demos, workshops and webinars. Prior to this, Juliane gained her PhD at Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany in Chromatin remodelling during a fungal‐bacterial interaction.